NUCIFIC BIO X4: Improve Digestive Health and Lose Weight

Digestive system support, appetite suppressant and metabolism booster in one bottle. Does NUCIFIC BIO X4 really work or is it a dud? Read our full review to find out more.



NUCIFIC BIO X4 takes an innovative approach to promoting both digestive health and weight loss by combining Probiotics with EGCG, Caralluma Fimbriata and a proprietary blend of Digestive Enzymes. BIO X4 refers to itself as a “Weight Management Probiotic”, which is correct when considering its ingredients and what benefits they have.

The Probiotics inside Unifi BIO X4 work to restore the perfect balance between good and bad bacteria in your gut, promoting bowel regularity and restoring and maintaining ideal digestive health. The Digestive Enzyme Blend works to support an easy digestion of carbs, proteins and fats. The metabolism also receives a boost from the potent Green Tea Extract (EGCG), while Caralluma Fimbriata is used in the potent formula of Nucific BIO X4 for its appetite suppressing properties. When combined, these four ingredients work together seamlessly to revitalize your digestive system and promote weight loss, offering you a new take on life.


How Does NUCIFIC BIO X4 Work?

Nucific claims the effectiveness of BIO X4 can be attributed to its patented formula. Probiotics improve your digestive health by balancing out your gut flora; restoring and maintaining the perfect ratio (80:20) between good and bad bacteria. Probiotics are a wonderful addition to your daily health regimen as they contribute to solving health issues such as constipation, bloating, gas or diarrhea. The Digestive Enzymes in Nucific Bio X4 ensure you get the maximum amount of nutrients from the foods you consume.

The weight loss effects of Nucific are brought by Caralluma Fimbriata, which is an appetite suppressant, and EGCG, which boosts metabolism. As you can see, BIO X4 takes a different approach when compared to other supplements, offering four main benefits: improved digestive system, higher quality fuel for your body, accelerated weight loss and curbed appetite.


NUCIFIC BIO X4 Ingredients

NUCIFIC BIO X4 does contain proven ingredients that have been shown to be effective for promoting digestive health, boosting metabolism and suppressing appetite. Let’s take a closer look at what’s inside this weight management probiotic:


BIO X4 ProbioticsProbiotics improve digestive system health by restoring and maintaining the perfect balance to your gut flora. These live bacteria have amazing abilities that can benefit your immune system, improve blood sugar, help you make smarter food choices and affect leptin sensitivity, a hormone that regulates your metabolic rate and appetite.

  • Lactobacillus acidophilus – supports overall digestion, helps with nutrient absorption, promotes immune health, offers gas, diarrhea and occasional cramping relief and is beneficial for urinary and vaginal health in women.
  • Lactobacillus rhamnosus – has been shown help with traveler’s diarrhea and improve vaginal and urinary health.
  • Lactobacillus plantarum – helps with overall digestion and detoxification.
  • Bifidobacterium lactis – enhances immunity, improves digestion and can lower cholesterol.
  • Bifidobacterium animalis – helps with Irritable Bowel Syndrome, discomfort, bloating and constipation.

BIO X4 Digestive EnzymesDigestive Enzymes

Digestive enzymes are enzymes that break down larger molecules into smaller building blocks so they can be absorbed more easily by the body.

  • Amylase (from Aspergilus Oryzae)
  • These digestive enzymes work on the starch in food, breaking it down into smaller carbohydrate molecules.
  • Bromelain
  • Bromelain is an enzyme that breaks down proteins to support healthy digestion. It helps with indigestion, upset stomach and heartburn.
  • Lipase (from Rhizopus Oryzae)
  • Lipase is an enzyme that breaks down dietary fats into smaller molecules: glycerol and fatty acids. It helps with the digestion of buttery fat in the foods you consume.

BIO X4 Caralluma FimbriataCaralluma Fimbriata

Caralluma Fimbriata is a type of edible cactus used by tribal Indians for its appetite suppressing properties. The working class in South India used it to enhance physical endurance. Caralluma Fimbriata works by inhibiting the hunger sensory mechanism of the hypothalamus, tricking the brain into thinking that the stomach is full, even if you haven’t eaten. Caralluma also inhibits fat synthesis by blocking the formation of building blocks of fat. Another benefit is it makes more energy available to the body by increasing the burning of fat.

In one placebo-controlled study, overweight participants were given either a placebo or 1g of Caralluma extract per day for a period of 60 days. At the end of the test, it showed a reduction in waist circumference and hunger levels for the Caralluma Fimbriata group.


EGCG is a powerful antioxidant found in green tea and contains hidden weight loss powers. EGCG increases metabolic rate, prevents the digestion of some carbs and may also reduce appetite.

In a study, researcher Kevin Maki lost around one-quarter pound per week by drinking 660mg of EGCG. The EGCG group in the study lost an average of 5.4 lbs. over a period of 12 weeks by drinking green tea and reducing calories. The group that followed a similar diet but drank black tea only lost 2.9 lbs. EGCG showed the participants using it lost 2.5 lb. more over the course of the study.


BIO X4 Results

Some users report back claiming they have experienced noticeable results in the first two weeks of using BIO X4. However, as everyone’s body is different, Nucific suggests you should give BIO X4 at least 30 days to experience the full list of benefits. The first thing most users experience is an improvement in their digestive system, naturally followed by a drop in weight.

Regardless of how many bottles your order (most customers choose the discounted 3-bottle package), you shouldn’t worry regarding the company. Nucific seems very confident about its product and thus offers a 90-day money back guarantee. If you’re not satisfied by the results, just send your bottles back within 90 days and get a full refund, no question asked. Nucific appears to be very confident.


Is Nucific BIO X4 Safe?

Nucific claims BIO X4 has no known side effects. Based on the ingredients, this should be true. It’s worth mentioning that the capsules are gluten-free and allergen free, so you can take them regardless of your dietary restrictions.

If you take BIO X4 on a daily basis but happen to miss a day, just continue as usual the following day. However, taking it consistently will help you build up an ideal and healthy level of beneficial bacteria, nutrients and enzymes in your body.


Who Makes BIO X4?

BIO X4 is made by Nucific, a company from California in the United States. The company is relatively young, but it has already established itself as a reputable and reliable manufacturer of dietary supplements. Nucific states it believes in an active lifestyle, but the company is aware that it is hard to find the time to exercise due to our busy schedules. This is why they aim to provide the essential nutrients we lack by enhancing our diets.

Many supplements and vitamins are made with synthetics and fillers, but Nucific says it manufactures their products in a serious fashion: “At Nucific we practice what we preach and provide you with an experience no other company can compete with.”

The company claims it bases their products on potent ingredients that are backed by scientific research; the products are tested for purity and potency by third-party labs; it uses renewable energy and recyclable materials; it makes its products in California; it offers 100% satisfaction through its 90-day money back guarantee.


How Do You Take NUCIFIC BIO X4?

The best results can be obtained by taking one BIO X4 capsule with each major meal. Doing so ensures you supply your system with the maximum amount of nutrients thanks to the Digestive Enzymes in Nucific BIO X4. Taking BIO X4 as indicated also helps the digestive system and boosts weight loss.



  • Promotes healthy digestive system
  • Boosts metabolism
  • Suppresses appetite
  • Helps you get the maximum amount of nutrients from the foods you consume
  • Gluten free, lactose free and vegetarian friendly
  • No filler, no binders, no animal byproducts
  • Made in the USA
  • Proven and tested ingredients
  • 90-day money back guarantee


Final Verdict on NUCIFIC BIO X4: 9/5/10

As long as you take one capsule with each major meal, Nucific BIO X4 should provide real results. The full 90-day money back guarantee is proof enough that the company is out there to provide a real Weight Management Probiotic and not just make a quick buck. We don’t usually give perfect ratings, but this is as close to perfect as possible as its approach to weight loss and digestive health is unique. This is not a basic probiotic supplement, it’s so much more than that.



One thought on “NUCIFIC BIO X4: Improve Digestive Health and Lose Weight

  • January 27, 2016 at 1:26 am

    Query: I’ve been taking
    Your digestive enzymes for a month with good results. I’ve even lost weight, which is listed as a possible side effect. I’m wondering about switching tothe Bio X, but it has fewer of the digestive enzymes. Can you advise me?


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